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During ferroptosis, the antioxidant axis of solute carrier family 7 member 11/glutathione peroxidase 4 (SLC7A11/GPX4) is deactivated, resulting in intracellular oxidative stress

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical metabolic coenzyme essential for redox reactions, mitochondrial function, and cellular energy generation

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Diterpenes Small intestine absorbs about 70% of the amount of cafestol and kahweol consumed (Ren et al., 2019

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This highlights the importance of a multifaceted approach to antioxidant therapy and motivates our exploration of the role of UA in neurodegenerative diseases